Menthol, found in peppermint oil, activates cold-sensitive receptors, providing a cooling sensation and potentially reducing pain perception
Menthol is an agonist for the TRPM8 receptors. When it permeates the skin, it activates the TRPM8 receptors
Camphor, derived from the wood of camphor trees, has a warming effect- Camphor can activate TRPM8 receptors as well as the vanilloid receptors TRPV1 and TRPV3, which produce the sensation of heat
They produce analgesic effects by acting on
sensory nerves
and modulating pain perceptionRoll on