Mechanism of Action

 

  • Zembrin® has a dual mechanism of action that includes phosphodiesterase-4 (PDE4) and serotonin (5-HT) reuptake inhibitionNeurotransmitter support, phosphodiesterase-4 (PDE4) and serotonin (5-HT) reuptake inhibition help sustain adequate serotonin levels in the brainIt decreases the impact of stressful events in the brain by reducing amygdala reactivity (stress centre of the brain)

Key Pointers

 
  • Dual mechanism of action: Selective serotonin (5-HT) reuptake and Phosphodiesterase-4 (PDE-4) inhibition
  • FSSAI approved with a health claim: 'Helps alleviating the anxiety symptoms’•
  • Proven safety and efficacy
  • Scientifically backed by 9 publications

Clinical Findings

 
  • 26.9% decrease in HAM-D score in 3 weeks which is the ‘Gold-Standard’ to assess the severity of depression
  • 16% decrease in HAM-A scores for anxiety
  • 24% & 24.8% increase in executive function & cognitive flexibility

Indication

Mood elevation Cognitive functions Add on therapy in Anxiety & Depression

Dosage Forms

  • Tablets

  • Capsules

  • Drops

  • Powder